| 2. Round | 13/07/2022 | Club León [U16] | - | UANL Tigres [U16] | 0:1 | ||||
| 4. Round | 16/07/2022 | Club Tijuana [U16] | - | UANL Tigres [U16] | 2:0 | ||||
| 8. Round | 13/08/2022 | Santos Laguna [U16] | - | UANL Tigres [U16] | 1:0 | ||||
| 11. Round | 03/09/2022 | Atlas Guadalajara [U16] | - | UANL Tigres [U16] | 2:0 | ||||
| 9. Round | 06/09/2022 | UANL Tigres [U16] | - | Atlas Guadalajara [U16] | 0:1 | ||||
| 12. Round | 10/09/2022 | UANL Tigres [U16] | - | Santos Laguna [U16] | 2:1 | ||||
| 13. Round | 17/09/2022 | Mazatlán FC [U16] | - | UANL Tigres [U16] | 1:2 | ||||
| 14. Round | 24/09/2022 | UANL Tigres [U16] | - | Atlético San Luis [U16] | 0:0 | ||||
| 15. Round | 01/10/2022 | CF Monterrey [U16] | - | UANL Tigres [U16] | 1:3 |  |
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| 18. Round | 22/10/2022 | UANL Tigres [U16] | - | Club León [U16] | 1:1 |
Mexico