| 1. Round | 07/08/2022 | Liverpool FC U21 | - | Manchester City U21 | 0:3 | ||||
| 2. Round | 14/08/2022 | Manchester City U21 | - | Leicester City U21 | 3:1 | ||||
| 3. Round | 21/08/2022 | Manchester City U21 | - | Tottenham Hotspur U21 | 0:0 | ||||
| 7. Round | 17/09/2022 | Manchester City U21 | - | Fulham FC U21 | 1:0 | ||||
| 8. Round | 02/10/2022 | Wolverhampton Wanderers U21 | - | Manchester City U21 | 1:3 | ||||
| 9. Round | 08/10/2022 | Manchester City U21 | - | Blackburn Rovers U21 | 1:3 | ||||
| 11. Round | 22/10/2022 | Manchester City U21 | - | Crystal Palace U21 | 3:3 | ||||
| 13. Round | 05/11/2022 | Manchester United U21 | - | Manchester City U21 | 1:6 | ||||
| 14. Round | 07/01/2023 | Manchester City U21 | - | Arsenal FC U21 | 6:0 | ||||
| 15. Round | 14/01/2023 | Manchester City U21 | - | Brighton & Hove Albion U21 | 2:1 | ||||
| 16. Round | 20/01/2023 | Leicester City U21 | - | Manchester City U21 | 0:0 | ||||
| 17. Round | 30/01/2023 | Crystal Palace U21 | - | Manchester City U21 | 0:5 | ||||
| 18. Round | 12/02/2023 | Manchester City U21 | - | Liverpool FC U21 | 3:1 | ||||
| 19. Round | 17/02/2023 | Fulham FC U21 | - | Manchester City U21 | 2:2 | ||||
| 10. Round | 06/05/2023 | Arsenal FC U21 | - | Manchester City U21 | 0:3 |
Netherlands