| 1. Round | 23/07/2021 | Tsarsko Selo Sofia | - | Cherno More Varna | 0:0 | ||||
| 2. Round | 30/07/2021 | Slavia Sofia | - | Tsarsko Selo Sofia | 0:0 |  |
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| 3. Round | 06/08/2021 | Tsarsko Selo Sofia | - | Botev Vratsa | 1:2 | |
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| 4. Round | 14/08/2021 | Levski Sofia | - | Tsarsko Selo Sofia | 3:1 | ||||
| 7. Round | 13/09/2021 | PFC Beroe | - | Tsarsko Selo Sofia | 1:0 | ||||
| 8. Round | 17/09/2021 | Tsarsko Selo Sofia | - | Lokomotiv Plovdiv | 0:2 | ||||
| 9. Round | 25/09/2021 | CSKA 1948 Sofia | - | Tsarsko Selo Sofia | 1:0 | ||||
| 11. Round | 16/10/2021 | PFC Ludogorets Razgrad | - | Tsarsko Selo Sofia | 4:0 | ||||
| 12. Round | 22/10/2021 | Tsarsko Selo Sofia | - | Lokomotiv Sofia | 2:0 | ||||
| 13. Round | 31/10/2021 | Pirin Blagoevgrad | - | Tsarsko Selo Sofia | 2:1 | ||||
| 14. Round | 06/11/2021 | Cherno More Varna | - | Tsarsko Selo Sofia | 1:1 |  |
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| 18. Round | 06/12/2021 | Arda Kardzhali | - | Tsarsko Selo Sofia | 2:0 | ||||
| 19. Round | 11/12/2021 | Botev Plovdiv | - | Tsarsko Selo Sofia | 2:1 | |
Serbia