| 1. Round | 29/01/2023 | General Caballero DJLM | - | Resistencia SC | 2:0 | ||||
| 2. Round | 05/02/2023 | Sportivo Luqueño | - | General Caballero DJLM | 1:1 | ||||
| 3. Round | 11/02/2023 | General Caballero DJLM | - | Club Nacional | 0:1 | ||||
| 4. Round | 19/02/2023 | Tacuary | - | General Caballero DJLM | 1:1 | ||||
| 5. Round | 26/02/2023 | General Caballero DJLM | - | Sportivo Trinidense | 1:4 |  |
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| 6. Round | 03/03/2023 | Guaireña FC | - | General Caballero DJLM | 0:0 | ||||
| 7. Round | 12/03/2023 | General Caballero DJLM | - | Club Olimpia | 1:2 | ||||
| 8. Round | 20/03/2023 | General Caballero DJLM | - | Cerro Porteño | 2:3 | ||||
| 9. Round | 31/03/2023 | Libertad | - | General Caballero DJLM | 1:0 | ||||
| 10. Round | 03/04/2023 | General Caballero DJLM | - | Sportivo Ameliano | 0:1 | ||||
| 18. Round | 17/05/2023 | Club Olimpia | - | General Caballero DJLM | 1:1 | ||||
| 19. Round | 20/05/2023 | Cerro Porteño | - | General Caballero DJLM | 1:2 | ||||
| 21. Round | 03/06/2023 | Sportivo Ameliano | - | General Caballero DJLM | 0:1 | ||||
| 22. Round | 10/06/2023 | General Caballero DJLM | - | Guaraní | 0:0 |
Paraguay