| 12. Round | 08/01/2022 | GS Kallithea | - | Panathinaikos II | 1:0 | ||||
| 14. Round | 16/01/2022 | GS Kallithea | - | Ergotelis | 3:2 | ||||
| 15. Round | 23/01/2022 | Asteras Vlachioti | - | GS Kallithea | 0:2 |  |
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| 11. Round | 23/02/2022 | PS Kalamata | - | GS Kallithea | 2:2 | ||||
| 21. Round | 27/02/2022 | AO Egaleo | - | GS Kallithea | 0:0 | ||||
| 13. Round | 02/03/2022 | AE Karaiskakis | - | GS Kallithea | 1:0 | ||||
| 22. Round | 06/03/2022 | GS Kallithea | - | Irodotos | 3:0 | ||||
| 24. Round | 13/03/2022 | GS Kallithea | - | AS Rhodos | 2:0 | ||||
| 25. Round | 20/03/2022 | AO Episkopi | - | GS Kallithea | 1:1 | ||||
| 31. Round | 13/04/2022 | Ergotelis | - | GS Kallithea | 0:2 | |
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| 32. Round | 17/04/2022 | GS Kallithea | - | Asteras Vlachioti | 5:1 |  |
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| 27. Round | 23/04/2022 | AEK Athen II | - | GS Kallithea | 0:3 |
Sweden