| 1. Round | 07/08/2021 | RFCU Luxemburg | - | Swift Hesperange | 0:3 | ||||
| 2. Round | 15/08/2021 | Swift Hesperange | - | Union Titus Pétange | 0:2 |  |
|||
| 7. Round | 22/09/2021 | CS FOLA Esch | - | Swift Hesperange | 2:1 | |
|||
| 8. Round | 26/09/2021 | Swift Hesperange | - | UNA Strassen | 0:1 | |
|||
| 9. Round | 17/10/2021 | Swift Hesperange | - | Progrès Niedercorn | 1:1 | |
|||
| 28. Round | 08/05/2022 | Swift Hesperange | - | Jeunesse Esch | 1:1 | |
|||
| 30. Round | 22/05/2022 | Swift Hesperange | - | RFCU Luxemburg | 2:0 |
Guinea