| 19. Round | 21/01/2006 | Sint-Truidense VV | - | Lierse SK (old) | 1:1 | ||||
| 20. Round | 28/01/2006 | Lierse SK (old) | - | KSK Beveren | 2:0 | ||||
| 21. Round | 03/02/2006 | Club Brugge KV | - | Lierse SK (old) | 3:1 | ||||
| 22. Round | 11/02/2006 | Lierse SK (old) | - | Sporting Lokeren | 2:0 | ||||
| 23. Round | 18/02/2006 | Sporting Charleroi | - | Lierse SK (old) | 0:1 | ||||
| 29. Round | 01/04/2006 | Cercle Brugge | - | Lierse SK (old) | 3:0 | ||||
| 30. Round | 08/04/2006 | Lierse SK (old) | - | Germinal Beerschot | 0:2 | ||||
| 32. Round | 22/04/2006 | Lierse SK (old) | - | Excelsior Mouscron | 2:0 | ||||
| 33. Round | 30/04/2006 | FC Brussels | - | Lierse SK (old) | 2:1 |  |
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| 34. Round | 05/05/2006 | Lierse SK (old) | - | KSV Roeselare | 1:0 |
Netherlands