| 1. Round | 23/02/2025 | Seattle Sounders | - | Charlotte FC | 2:2 | ||||
| 2. Round | 01/03/2025 | Charlotte FC | - | Atlanta United FC | 2:0 | ||||
| 3. Round | 09/03/2025 | Inter Miami CF | - | Charlotte FC | 1:0 | ||||
| 4. Round | 15/03/2025 | Charlotte FC | - | FC Cincinnati | 2:0 | ||||
| 5. Round | 22/03/2025 | Charlotte FC | - | San Jose Earthquakes | 4:1 | ||||
| 6. Round | 29/03/2025 | Colorado Rapids | - | Charlotte FC | 2:0 | ||||
| 7. Round | 05/04/2025 | Charlotte FC | - | Nashville SC | 2:1 |  |
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| 8. Round | 13/04/2025 | CF Montréal | - | Charlotte FC | 0:1 |
England