| 11. Round | 10/09/2021 | Gimnasia de La Plata II | - | Vélez Sarsfield II | 2:3 | ||||
| 15. Round | 08/10/2021 | Newell's Old Boys II | - | Vélez Sarsfield II | 0:0 | ||||
| 17. Round | 19/10/2021 | Central Córdoba SdE II | - | Vélez Sarsfield II | 2:0 | ||||
| 19. Round | 29/10/2021 | Banfield II | - | Vélez Sarsfield II | 1:2 | ||||
| 9. Round | 11/11/2021 | Vélez Sarsfield II | - | Godoy Cruz II | 3:0 | ||||
| 23. Round | 29/11/2021 | Estudiantes II | - | Vélez Sarsfield II | 2:3 |
Argentina