| 1. Round | 31/07/2011 | General Caballero ZC | - | Independiente CG | 2:1 |  |
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| 2. Round | 07/08/2011 | Club Nacional | - | General Caballero ZC | 3:0 | ||||
| 3. Round | 14/08/2011 | General Caballero ZC | - | Tacuary | 1:1 | |
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| 4. Round | 20/08/2011 | Club Olimpia | - | General Caballero ZC | 2:1 | |
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| 7. Round | 09/09/2011 | General Caballero ZC | - | Libertad | 0:3 | ||||
| 8. Round | 18/09/2011 | General Caballero ZC | - | Club Rubio Ñu | 0:1 | ||||
| 9. Round | 24/09/2011 | Sol de América | - | General Caballero ZC | 4:0 | |
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| 10. Round | 28/09/2011 | General Caballero ZC | - | Cerro Porteño | 2:4 | ||||
| 18. Round | 27/11/2011 | Libertad | - | General Caballero ZC | 1:0 | |
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| 19. Round | 30/11/2011 | Club Rubio Ñu | - | General Caballero ZC | 0:2 | ||||
| 20. Round | 04/12/2011 | General Caballero ZC | - | Sol de América | 1:2 |
Paraguay