| 2. Round | 26/01/2019 | Club Olimpia | - | San Lorenzo | 2:0 | ||||
| 3. Round | 03/02/2019 | Sportivo Luqueño | - | Club Olimpia | 1:5 | ||||
| 5. Round | 09/02/2019 | Sol de América | - | Club Olimpia | 0:1 | ||||
| 1. Round | 13/02/2019 | Club Nacional | - | Club Olimpia | 2:4 | ||||
| 7. Round | 24/02/2019 | Libertad | - | Club Olimpia | 2:3 | ||||
| 8. Round | 27/02/2019 | Club Olimpia | - | Deportivo Capiatá | 3:0 |  |
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| 9. Round | 02/03/2019 | General Díaz | - | Club Olimpia | 0:2 | |
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| 10. Round | 09/03/2019 | Club Olimpia | - | River Plate | 0:0 | |
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| 11. Round | 17/03/2019 | Guaraní | - | Club Olimpia | 1:5 | |
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| 12. Round | 24/03/2019 | Club Olimpia | - | Club Nacional | 0:0 | ||||
| 13. Round | 30/03/2019 | San Lorenzo | - | Club Olimpia | 1:4 | |
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| 16. Round | 13/04/2019 | Club Olimpia | - | Sol de América | 4:0 | |
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| 17. Round | 20/04/2019 | Cerro Porteño | - | Club Olimpia | 1:3 | ||||
| 19. Round | 01/05/2019 | Deportivo Capiatá | - | Club Olimpia | 2:2 | |
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| 15. Round | 04/05/2019 | Deportivo Santaní | - | Club Olimpia | 0:6 | |
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| 22. Round | 18/05/2019 | Club Olimpia | - | Guaraní | 2:0 |
Paraguay