| 1. Round | 04/07/2020 | FC Milsami | - | CS Petrocub | 0:0 | ||||
| 2. Round | 09/07/2020 | Dacia Buiucani | - | FC Milsami | 0:0 | ||||
| 3. Round | 13/07/2020 | FC Milsami | - | Speranţa Nisporeni | 3:0 | ||||
| 4. Round | 19/07/2020 | FC Sfîntul Gheorghe | - | FC Milsami | 3:1 | ||||
| 5. Round | 23/07/2020 | FC Milsami | - | FC Sheriff | 0:1 |  |
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| 6. Round | 27/07/2020 | FC Zimbru | - | FC Milsami | 0:1 | ||||
| 7. Round | 31/07/2020 | FC Milsami | - | FC Codru Lozova | 3:1 | |
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| 9. Round | 13/09/2020 | FC Floreşti | - | FC Milsami | 0:4 |  |
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| 10. Round | 19/09/2020 | CS Petrocub | - | FC Milsami | 1:2 | |
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| 11. Round | 22/09/2020 | FC Milsami | - | Dacia Buiucani | 2:0 | |
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| 12. Round | 26/09/2020 | Speranţa Nisporeni | - | FC Milsami | 0:1 | ||||
| 21. Round | 20/02/2021 | FC Milsami | - | Speranţa Nisporeni | 3:0 | ||||
| 24. Round | 07/03/2021 | FC Zimbru | - | FC Milsami | 1:2 | ||||
| 25. Round | 12/03/2021 | FC Milsami | - | FC Codru Lozova | 7:2 | ||||
| 26. Round | 19/03/2021 | FC Milsami | - | Dinamo-Auto | 2:2 | ||||
| 27. Round | 12/04/2021 | FC Floreşti | - | FC Milsami | 2:5 | ||||
| 29. Round | 24/04/2021 | FC Milsami | - | Dacia Buiucani | 3:0 | ||||
| 30. Round | 30/04/2021 | Speranţa Nisporeni | - | FC Milsami | 0:4 | ||||
| 33. Round | 15/05/2021 | FC Milsami | - | FC Zimbru | 2:1 |
Moldova
Russia