| 4. Round | 14/09/2021 | Vejle BK [Youth B] | - | FC Midtjylland [Youth B] | 2:0 | ||||
| 6. Round | 24/09/2021 | Silkeborg IF [Youth B] | - | FC Midtjylland [Youth B] | 0:2 | ||||
| 10. Round | 30/10/2021 | FC Midtjylland [Youth B] | - | Brøndby IF [Youth B] | 3:1 |  |
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| 8. Round | 14/11/2021 | Odense BK [Youth B] | - | FC Midtjylland [Youth B] | 2:0 | ||||
| 5. Round | 11/12/2021 | FC Midtjylland [Youth B] | - | SønderjyskE [Youth B] | 4:0 | ||||
| 22. Round | 09/03/2022 | FC Midtjylland [Youth B] | - | Vejle BK [Youth B] | 3:2 | |
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| 16. Round | 12/03/2022 | FC Nordsjælland [Youth B] | - | FC Midtjylland [Youth B] | 0:2 | ||||
| 20. Round | 23/04/2022 | Aarhus GF [Youth B] | - | FC Midtjylland [Youth B] | 1:2 | ||||
| 23. Round | 14/05/2022 | Esbjerg fB [Youth B] | - | FC Midtjylland [Youth B] | 2:4 | ||||
| 25. Round | 11/06/2022 | FC Midtjylland [Youth B] | - | Lyngby BK [Youth B] | 2:1 | |
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| 26. Round | 18/06/2022 | AC Horsens [Youth B] | - | FC Midtjylland [Youth B] | 1:10 | |
Denmark