| 1. Round | 21/07/2019 | CF América | - | CF Monterrey | 4:2 |  |
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| 2. Round | 28/07/2019 | Club León | - | CF América | 0:0 |  |
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| 3. Round | 04/08/2019 | CF América | - | Club Tijuana | 3:1 | ||||
| 15. Round | 27/10/2019 | CF América | - | Puebla FC | 2:0 | |
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| 16. Round | 30/10/2019 | Atlético San Luis | - | CF América | 0:1 | ||||
| 17. Round | 03/11/2019 | CF América | - | Santos Laguna | 1:2 | ||||
| 18. Round | 09/11/2019 | CD Veracruz | - | CF América | 0:5 | |
Chile