| 1. Round | 18/08/2024 | River Plate | - | Nacional | 3:3 | ||||
| 4. Round | 22/09/2024 | Boston River | - | River Plate | 3:1 | ||||
| 5. Round | 29/09/2024 | River Plate | - | Fénix | 4:3 | ||||
| 6. Round | 04/10/2024 | River Plate | - | Liverpool | 1:1 | ||||
| 7. Round | 13/10/2024 | Montevideo Wanderers | - | River Plate | 0:1 | ||||
| 8. Round | 17/10/2024 | River Plate | - | Defensor Sporting | 0:1 | ||||
| 10. Round | 03/11/2024 | River Plate | - | Peñarol | 0:1 |  |
|||
| 11. Round | 09/11/2024 | Cerro Largo | - | River Plate | 1:0 | |
|||
| 12. Round | 13/11/2024 | River Plate | - | Miramar Misiones | 0:0 | ||||
| 13. Round | 19/11/2024 | Rampla Juniors | - | River Plate | 0:3 | ||||
| 14. Round | 26/11/2024 | River Plate | - | CA Cerro | 1:0 | ||||
| 15. Round | 01/12/2024 | Racing | - | River Plate | 2:0 |
Uruguay