| 1. Round | 23/02/2025 | Santa Cruz | - | Rangers | 0:3 | ||||
| 2. Round | 28/02/2025 | Recoleta | - | Santa Cruz | 3:2 |  |
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| 3. Round | 09/03/2025 | San Luis | - | Santa Cruz | 1:1 | |
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| 4. Round | 16/03/2025 | Santa Cruz | - | Deportes Concepción | 2:0 | ||||
| 5. Round | 28/03/2025 | Universidad de Concepción | - | Santa Cruz | 1:0 | ||||
| 6. Round | 13/04/2025 | Santa Cruz | - | Santiago Morning | 0:2 | ||||
| 7. Round | 18/04/2025 | Curicó Unido | - | Santa Cruz | 2:3 | ||||
| 8. Round | 26/04/2025 | Santa Cruz | - | Deportes Copiapó | 0:1 | ||||
| 9. Round | 05/05/2025 | CD Magallanes | - | Santa Cruz | 3:0 | ||||
| 10. Round | 18/05/2025 | Santa Cruz | - | Santiago Wanderers | 2:2 | ||||
| 11. Round | 23/05/2025 | Cobreloa | - | Santa Cruz | 1:1 | |
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| 12. Round | 01/06/2025 | Santa Cruz | - | Unión San Felipe | 1:1 |
Chile