| 1. Round | 20/08/2017 | Liverpool | - | River Plate | 0:4 | ||||
| 4. Round | 12/09/2017 | River Plate | - | Nacional | 2:1 | ||||
| 7. Round | 14/10/2017 | Defensor Sporting | - | River Plate | 2:1 | ||||
| 8. Round | 04/11/2017 | River Plate | - | Sud América | 1:2 |  |
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| 9. Round | 08/11/2017 | Juventud de Las Piedras | - | River Plate | 1:0 | ||||
| 10. Round | 11/11/2017 | River Plate | - | Danubio | 1:1 | ||||
| 11. Round | 15/11/2017 | Plaza Colonia | - | River Plate | 2:3 | ||||
| 12. Round | 18/11/2017 | CA Cerro | - | River Plate | 2:2 | |
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| 13. Round | 22/11/2017 | River Plate | - | Peñarol | 2:1 | |
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| 15. Round | 03/12/2017 | River Plate | - | El Tanque Sisley | 1:0 |
Uruguay