| 1. Round | 07/01/2025 | CF América [Women] | - | Cruz Azul [Women] | 2:1 | ||||
| 3. Round | 16/01/2025 | Club Necaxa [Women] | - | CF América [Women] | 0:5 |  |
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| 4. Round | 22/01/2025 | Atlas Guadalajara [Women] | - | CF América [Women] | 0:3 | |
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| 5. Round | 25/01/2025 | CF América [Women] | - | Club León [Women] | 5:0 | ||||
| 6. Round | 04/02/2025 | CF Pachuca [Women] | - | CF América [Women] | 2:1 | ||||
| 8. Round | 11/02/2025 | CF América [Women] | - | CF Monterrey [Women] | 3:2 | ||||
| 9. Round | 15/02/2025 | Pumas UNAM [Women] | - | CF América [Women] | 1:3 | ||||
| 11. Round | 08/03/2025 | Deportivo Guadalajara [Women] | - | CF América [Women] | 1:1 | ||||
| 12. Round | 12/03/2025 | CF América [Women] | - | Puebla FC [Women] | 7:0 | ||||
| 13. Round | 17/03/2025 | FC Juárez [Women] | - | CF América [Women] | 1:1 | ||||
| 14. Round | 23/03/2025 | CF América [Women] | - | UANL Tigres [Women] | 2:1 | ||||
| 15. Round | 29/03/2025 | Santos Laguna [Women] | - | CF América [Women] | 0:3 | |
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| 16. Round | 14/04/2025 | CF América [Women] | - | Club Tijuana [Women] | 4:1 | ||||
| 17. Round | 19/04/2025 | Deportivo Toluca [Women] | - | CF América [Women] | 4:3 |
USA
Mexico