| 1. Round | 22/08/2021 | VV Dongen | - | JOS Watergraafsmeer | 1:1 |  |
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| 2. Round | 29/08/2021 | JOS Watergraafsmeer | - | HVV Hollandia | 1:0 | |
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| 3. Round | 05/09/2021 | HSC'21 | - | JOS Watergraafsmeer | 1:5 | |
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| 4. Round | 12/09/2021 | JOS Watergraafsmeer | - | USV Hercules | 1:4 | ||||
| 7. Round | 03/10/2021 | VV Hoogland | - | JOS Watergraafsmeer | 3:1 | ||||
| 8. Round | 10/10/2021 | JOS Watergraafsmeer | - | OSS '20 | 3:3 | |
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| 9. Round | 17/10/2021 | RKSV Groene Ster | - | JOS Watergraafsmeer | 1:0 | ||||
| 10. Round | 31/10/2021 | JOS Watergraafsmeer | - | Unitas Gorinchem | 2:0 | ||||
| 11. Round | 07/11/2021 | VV UNA | - | JOS Watergraafsmeer | 1:4 | |
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| 12. Round | 14/11/2021 | JOS Watergraafsmeer | - | ADO '20 | 1:3 | ||||
| 15. Round | 20/02/2022 | VV Gemert | - | JOS Watergraafsmeer | 4:3 | |
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| 16. Round | 27/02/2022 | JOS Watergraafsmeer | - | OFC Oostzaan | 5:4 | ||||
| 19. Round | 20/03/2022 | JOS Watergraafsmeer | - | Quick Den Haag | 1:2 | ||||
| 17. Round | 30/03/2022 | EVV | - | JOS Watergraafsmeer | 0:4 | |
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| 23. Round | 03/04/2022 | JOS Watergraafsmeer | - | RKSV Groene Ster | 2:3 | ||||
| 26. Round | 18/04/2022 | HVV Hollandia | - | JOS Watergraafsmeer | 0:1 |
Netherlands