| 17. Round | 13/10/2021 | FK Krasnodar 2 | - | Torpedo Moskva | 1:1 | ||||
| 20. Round | 31/10/2021 | Alania Vladikavkaz | - | FK Krasnodar 2 | 2:1 | ||||
| 24. Round | 21/11/2021 | Volgar Astrakhan | - | FK Krasnodar 2 | 0:0 | ||||
| 27. Round | 12/03/2022 | FK Krasnodar 2 | - | Fakel Voronezh | 1:2 | ||||
| 28. Round | 20/03/2022 | FK Tom Tomsk | - | FK Krasnodar 2 | 1:2 | ||||
| 29. Round | 26/03/2022 | FK Krasnodar 2 | - | FK Orenburg | 5:2 | ||||
| 30. Round | 02/04/2022 | Akron Tolyatti | - | FK Krasnodar 2 | 1:0 | ||||
| 31. Round | 06/04/2022 | FK Krasnodar 2 | - | FK Neftekhimik | 2:0 | ||||
| 32. Round | 10/04/2022 | Rotor Volgograd | - | FK Krasnodar 2 | 1:2 | ||||
| 33. Round | 16/04/2022 | FK Krasnodar 2 | - | FK Kamaz | 4:1 | ||||
| 35. Round | 30/04/2022 | Torpedo Moskva | - | FK Krasnodar 2 | 2:0 | ||||
| 36. Round | 07/05/2022 | FK Krasnodar 2 | - | Enisey Krasnoyarsk | 4:0 | ||||
| 38. Round | 21/05/2022 | FK Krasnodar 2 | - | Spartak Moskva 2 | 1:3 |
Russia