| 1. Round | 24/07/2021 | Dinamo Stavropol | - | FK Mashuk KMV | 1:1 |  |
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| 3. Round | 06/08/2021 | FK Yessentuki | - | FK Mashuk KMV | 0:2 | ||||
| 4. Round | 15/08/2021 | FK Mashuk KMV | - | FK Biolog Novokubansk | 2:0 | ||||
| 20. Round | 06/03/2022 | FK Biolog Novokubansk | - | FK Mashuk KMV | 2:1 | ||||
| 21. Round | 14/03/2022 | FK Mashuk KMV | - | FK Legion Dynamo Makhachkala | 2:2 | ||||
| 23. Round | 27/03/2022 | Spartak Nalchik | - | FK Mashuk KMV | 1:3 | ||||
| 24. Round | 03/04/2022 | FK Mashuk KMV | - | FK Chayka | 0:0 | |
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| 25. Round | 10/04/2022 | Anzhi Makhachkala | - | FK Mashuk KMV | 1:1 | ||||
| 26. Round | 17/04/2022 | FK Mashuk KMV | - | FK Druzhba | 0:1 | ||||
| 28. Round | 30/04/2022 | FK Mashuk KMV | - | Kuban-Holding Pavlovskaya | 3:3 | ||||
| 30. Round | 12/05/2022 | FK Mashuk KMV | - | FK Dinamo Makhachkala | 0:2 | ||||
| 31. Round | 16/05/2022 | Rotor-2 Volgograd | - | FK Mashuk KMV | 2:2 | ||||
| 32. Round | 22/05/2022 | FK Mashuk KMV | - | FK Tuapse | 1:3 | ||||
| 33. Round | 29/05/2022 | FK SKA Rostov | - | FK Mashuk KMV | 6:3 |
Russia