| 1. Round | 24/07/2021 | Anzhi Makhachkala | - | Rotor-2 Volgograd | 3:0 | ||||
| 2. Round | 01/08/2021 | FK Druzhba | - | Rotor-2 Volgograd | 0:2 | ||||
| 3. Round | 07/08/2021 | Rotor-2 Volgograd | - | Alania-2 Vladikavkaz | 1:1 | ||||
| 5. Round | 21/08/2021 | Rotor-2 Volgograd | - | Forte Taganrog | 1:2 | ||||
| 6. Round | 29/08/2021 | FK Dinamo Makhachkala | - | Rotor-2 Volgograd | 2:0 | ||||
| 8. Round | 08/09/2021 | Rotor-2 Volgograd | - | FK Tuapse | 0:1 | ||||
| 12. Round | 05/10/2021 | Rotor-2 Volgograd | - | FK Yessentuki | 6:0 | ||||
| 16. Round | 31/10/2021 | Rotor-2 Volgograd | - | Spartak Nalchik | 0:3 | ||||
| 17. Round | 06/11/2021 | FK Chayka | - | Rotor-2 Volgograd | 3:1 | ||||
| 19. Round | 20/11/2021 | Alania-2 Vladikavkaz | - | Rotor-2 Volgograd | 2:2 | ||||
| 25. Round | 11/04/2022 | Rotor-2 Volgograd | - | FK SKA Rostov | 0:7 |  |
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| 27. Round | 24/04/2022 | Rotor-2 Volgograd | - | Chernomorets Novorossisk | 0:5 | ||||
| 29. Round | 06/05/2022 | Rotor-2 Volgograd | - | FK Biolog Novokubansk | 1:3 | |
Russia