| 1. Round | 20/07/2019 | Atlético San Luis | - | Pumas UNAM | 0:2 | ||||
| 2. Round | 28/07/2019 | Atlético San Luis | - | CF Monterrey | 1:0 |  |
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| 4. Round | 11/08/2019 | Deportivo Guadalajara | - | Atlético San Luis | 3:0 | ||||
| 5. Round | 17/08/2019 | Atlético San Luis | - | UANL Tigres | 1:1 | |
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| 6. Round | 24/08/2019 | CD Veracruz | - | Atlético San Luis | 1:2 | ||||
| 7. Round | 28/08/2019 | Atlético San Luis | - | Monarcas Morelia | 1:1 |  |
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| 9. Round | 14/09/2019 | Puebla FC | - | Atlético San Luis | 1:3 | |
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| 11. Round | 27/09/2019 | Deportivo Toluca | - | Atlético San Luis | 3:1 | ||||
| 14. Round | 20/10/2019 | Atlético San Luis | - | Gallos Blancos | 0:2 | ||||
| 19. Round | 24/11/2019 | Cruz Azul | - | Atlético San Luis | 3:1 |
Mexico