| 1. Round | 06/08/2005 | Standard Liège | - | Lierse SK (old) | 3:1 | ||||
| 2. Round | 14/08/2005 | Lierse SK (old) | - | Sint-Truidense VV | 1:0 |  |
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| 3. Round | 20/08/2005 | KSK Beveren | - | Lierse SK (old) | 4:1 | ||||
| 8. Round | 25/09/2005 | Lierse SK (old) | - | RSC Anderlecht | 0:0 | ||||
| 9. Round | 01/10/2005 | KAA Gent | - | Lierse SK (old) | 1:1 | ||||
| 10. Round | 15/10/2005 | Lierse SK (old) | - | SV Zulte Waregem | 0:2 | ||||
| 12. Round | 29/10/2005 | Lierse SK (old) | - | Cercle Brugge | 0:4 | ||||
| 13. Round | 05/11/2005 | Germinal Beerschot | - | Lierse SK (old) | 4:0 | ||||
| 14. Round | 20/11/2005 | Lierse SK (old) | - | KRC Genk | 1:2 |
Croatia