| 1. Round | 20/09/2020 | 1. FC Heidenheim 1846 | - | Eintracht Braunschweig | 2:0 | ||||
| 2. Round | 27/09/2020 | FC St. Pauli | - | 1. FC Heidenheim 1846 | 4:2 | ||||
| 9. Round | 29/11/2020 | 1. FC Heidenheim 1846 | - | Hamburger SV | 3:2 | ||||
| 15. Round | 08/01/2021 | SV Sandhausen | - | 1. FC Heidenheim 1846 | 4:0 | ||||
| 16. Round | 17/01/2021 | 1. FC Heidenheim 1846 | - | SV Darmstadt 98 | 3:0 | ||||
| 18. Round | 26/01/2021 | Eintracht Braunschweig | - | 1. FC Heidenheim 1846 | 1:0 | ||||
| 21. Round | 13/02/2021 | 1. FC Heidenheim 1846 | - | Erzgebirge Aue | 2:0 | ||||
| 20. Round | 23/02/2021 | SC Paderborn 07 | - | 1. FC Heidenheim 1846 | 2:2 | ||||
| 24. Round | 05/03/2021 | Würzburger Kickers | - | 1. FC Heidenheim 1846 | 1:2 | ||||
| 34. Round | 23/05/2021 | 1. FC Heidenheim 1846 | - | Karlsruher SC | 1:2 |
Germany