| 1. Round | 05/02/2022 | Sport Huancayo | - | Sporting Cristal | 1:0 | ||||
| 2. Round | 13/02/2022 | Sporting Cristal | - | FBC Melgar | 2:2 | ||||
| 4. Round | 25/02/2022 | Sporting Cristal | - | Universidad Técnica | 3:2 | ||||
| 5. Round | 06/03/2022 | Alianza Lima | - | Sporting Cristal | 0:1 | ||||
| 6. Round | 13/03/2022 | Sporting Cristal | - | Academia Cantolao | 2:2 | ||||
| 7. Round | 20/03/2022 | Carlos Stein | - | Sporting Cristal | 1:1 | ||||
| 8. Round | 01/04/2022 | Sporting Cristal | - | Universidad San Martín | 4:1 | ||||
| 9. Round | 09/04/2022 | Universidad Cesar Vallejo | - | Sporting Cristal | 2:0 | ||||
| 10. Round | 16/04/2022 | Sporting Cristal | - | Deportivo Municipal | 6:4 | ||||
| 11. Round | 23/04/2022 | Cienciano | - | Sporting Cristal | 0:1 | ||||
| 12. Round | 30/04/2022 | Sporting Cristal | - | Deportivo Binacional | 1:0 |  |
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| 15. Round | 22/05/2022 | Universitario de Deportes | - | Sporting Cristal | 1:1 | ||||
| 16. Round | 05/06/2022 | Sporting Cristal | - | Sport Boys | 3:0 | ||||
| 17. Round | 19/06/2022 | Atlético Grau | - | Sporting Cristal | 0:2 |  |
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| 18. Round | 25/06/2022 | Sporting Cristal | - | Alianza Atlético | 1:0 | ||||
| 19. Round | 03/07/2022 | Mannucci | - | Sporting Cristal | 1:3 |
Argentina
Chile