| 1. Round | 29/08/2021 | Bnei Sachnin FC | - | Maccabi Tel Aviv | 3:1 | ||||
| 2. Round | 11/09/2021 | Maccabi Tel Aviv | - | Maccabi Petach-Tikva | 1:1 | ||||
| 3. Round | 18/09/2021 | Maccabi Tel Aviv | - | Maccabi Haifa | 2:1 | ||||
| 4. Round | 25/09/2021 | Hapoel Be'er Sheva | - | Maccabi Tel Aviv | 2:0 | ||||
| 5. Round | 03/10/2021 | Maccabi Tel Aviv | - | Hapoel Jerusalem | 1:0 | ||||
| 6. Round | 16/10/2021 | Maccabi Netanya | - | Maccabi Tel Aviv | 4:2 | ||||
| 7. Round | 25/10/2021 | Maccabi Tel Aviv | - | FC Ashdod | 0:2 | ||||
| 8. Round | 30/10/2021 | Ironi Kiryat Shmona | - | Maccabi Tel Aviv | 1:3 |  |
|||
| 11. Round | 01/12/2021 | Maccabi Tel Aviv | - | Hapoel Nof HaGalil | 1:1 | ||||
| 13. Round | 13/12/2021 | Maccabi Tel Aviv | - | Hapoel Hadera | 3:0 | ||||
| 14. Round | 22/12/2021 | Maccabi Tel Aviv | - | Bnei Sachnin FC | 1:1 |  |
|||
| 17. Round | 08/01/2022 | Maccabi Tel Aviv | - | Hapoel Be'er Sheva | 1:0 | |
|||
| 18. Round | 15/01/2022 | Hapoel Jerusalem | - | Maccabi Tel Aviv | 1:3 | ||||
| 19. Round | 22/01/2022 | Maccabi Tel Aviv | - | Maccabi Netanya | 2:2 |
Israel