| 3. Round | 26/03/2016 | General Díaz | - | Guaraní | 3:2 | ||||
| 14. Round | 11/04/2016 | Guaraní | - | General Díaz | 3:0 | ||||
| 17. Round | 27/04/2016 | General Caballero ZC | - | Guaraní | 0:1 |  |
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| 19. Round | 05/05/2016 | Guaraní | - | Club Rubio Ñu | 3:1 | ||||
| 20. Round | 10/05/2016 | Club Olimpia | - | Guaraní | 3:2 | |
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| 21. Round | 15/05/2016 | Guaraní | - | Sol de América | 2:1 | |
Paraguay