| 18. Round | 22/08/2010 | Spartak Vladikavkaz | - | Anzhi Makhachkala | 0:0 | ||||
| 19. Round | 30/08/2010 | Anzhi Makhachkala | - | Sibir Novosibirsk | 1:0 | ||||
| 20. Round | 12/09/2010 | FK Rostov | - | Anzhi Makhachkala | 1:0 | ||||
| 21. Round | 19/09/2010 | Anzhi Makhachkala | - | Rubin Kazan | 0:1 | ||||
| 22. Round | 27/09/2010 | Krylia Sovetov | - | Anzhi Makhachkala | 3:0 |  |
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| 23. Round | 03/10/2010 | Anzhi Makhachkala | - | Spartak Moskva | 0:1 | ||||
| 26. Round | 31/10/2010 | Anzhi Makhachkala | - | Lokomotiv Moskva | 0:1 | ||||
| 29. Round | 20/11/2010 | Anzhi Makhachkala | - | FK Saturn | 1:2 |
Georgia