1. Round | 17/01/2010 | CF América | - | Club San Luis | 5:1 | ||||
2. Round | 24/01/2010 | Atlante | - | Club San Luis | 2:3 | ||||
3. Round | 31/01/2010 | Club San Luis | - | Monarcas Morelia | 0:2 | ||||
6. Round | 18/02/2010 | Puebla FC | - | Club San Luis | 1:0 | ||||
7. Round | 21/02/2010 | Club San Luis | - | Atlas Guadalajara | 3:1 | ||||
8. Round | 28/02/2010 | Deportivo Guadalajara | - | Club San Luis | 2:0 | ||||
9. Round | 07/03/2010 | Club San Luis | - | Cruz Azul | 1:2 | ||||
10. Round | 13/03/2010 | Jaguares Chiapas | - | Club San Luis | 1:1 | ||||
11. Round | 21/03/2010 | Club San Luis | - | Deportivo Toluca | 2:3 | ||||
12. Round | 28/03/2010 | Pumas UNAM | - | Club San Luis | 0:0 | ||||
13. Round | 04/04/2010 | Club San Luis | - | UANL Tigres | 0:3 | ||||
14. Round | 10/04/2010 | CF Monterrey | - | Club San Luis | 1:1 | ||||
15. Round | 15/04/2010 | Club San Luis | - | Estudiantes Tecos | 1:1 | ||||
16. Round | 20/04/2010 | Santos Laguna | - | Club San Luis | 2:1 |