| 1. Round | 19/07/2021 | Central Córdoba SdE II | - | Banfield II | 1:2 | ||||
| 2. Round | 23/07/2021 | San Lorenzo II | - | Central Córdoba SdE II | 1:0 | ||||
| 3. Round | 27/07/2021 | Central Córdoba SdE II | - | Talleres de Córdoba II | 1:2 | ||||
| 22. Round | 24/11/2021 | Newell's Old Boys II | - | Central Córdoba SdE II | 1:1 | ||||
| 23. Round | 29/11/2021 | Central Córdoba SdE II | - | Arsenal de Sarandí II | 1:2 |
Argentina