| 1. Round | 12/08/2000 | Rosario Central | - | Almagro | 1:1 |  |
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| 3. Round | 19/08/2000 | Rosario Central | - | Lanús | 1:1 | ||||
| 4. Round | 26/08/2000 | River Plate | - | Rosario Central | 4:1 | ||||
| 5. Round | 05/09/2000 | Rosario Central | - | Vélez Sarsfield | 2:2 | |
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| 8. Round | 22/09/2000 | Rosario Central | - | Independiente | 1:1 | ||||
| 9. Round | 30/09/2000 | Talleres de Córdoba | - | Rosario Central | 2:0 | |
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| 10. Round | 14/10/2000 | Rosario Central | - | CA Los Andes | 6:2 | ||||
| 11. Round | 21/10/2000 | San Lorenzo | - | Rosario Central | 4:1 | ||||
| 12. Round | 27/10/2000 | Rosario Central | - | Chacarita Juniors | 1:0 | |
Argentina