| 1. Round | 28/01/2006 | Olimpo de Bahía Blanca | - | Rosario Central | 0:0 |  |
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| 2. Round | 01/02/2006 | Rosario Central | - | Boca Juniors | 1:2 | ||||
| 3. Round | 05/02/2006 | Gimnasia de Jujuy | - | Rosario Central | 1:0 | |
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| 4. Round | 12/02/2006 | Lanús | - | Rosario Central | 2:0 | ||||
| 6. Round | 26/02/2006 | San Lorenzo | - | Rosario Central | 0:0 | ||||
| 7. Round | 01/03/2006 | Rosario Central | - | Argentinos Juniors | 1:1 | ||||
| 9. Round | 11/03/2006 | Rosario Central | - | Racing Club | 1:1 | |
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| 10. Round | 19/03/2006 | Quilmes | - | Rosario Central | 1:1 |  |
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| 11. Round | 26/03/2006 | Rosario Central | - | Tiro Federal de Rosario | 3:0 | |
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| 13. Round | 02/04/2006 | Rosario Central | - | Newell's Old Boys | 0:0 | |
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| 14. Round | 09/04/2006 | Banfield | - | Rosario Central | 2:0 | |
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| 15. Round | 16/04/2006 | Rosario Central | - | Colón de Santa Fe | 2:0 | |
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| 16. Round | 23/04/2006 | Arsenal de Sarandí | - | Rosario Central | 1:1 | ||||
| 17. Round | 30/04/2006 | Rosario Central | - | Vélez Sarsfield | 1:0 | |
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| 18. Round | 07/05/2006 | Estudiantes | - | Rosario Central | 1:1 | ||||
| 19. Round | 14/05/2006 | Rosario Central | - | Independiente | 2:0 |
Argentina