| 1. Round | 16/08/2008 | Energie Cottbus | - | 1899 Hoffenheim | 0:3 | ||||
| 2. Round | 23/08/2008 | 1899 Hoffenheim | - | Bor. Mönchengladbach | 1:0 |  |
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| 3. Round | 30/08/2008 | Bayer Leverkusen | - | 1899 Hoffenheim | 5:2 | ||||
| 4. Round | 13/09/2008 | 1899 Hoffenheim | - | VfB Stuttgart | 0:0 | ||||
| 5. Round | 21/09/2008 | 1899 Hoffenheim | - | Borussia Dortmund | 4:1 | ||||
| 6. Round | 27/09/2008 | Werder Bremen | - | 1899 Hoffenheim | 5:4 | ||||
| 12. Round | 09/11/2008 | Hertha BSC | - | 1899 Hoffenheim | 1:0 | ||||
| 14. Round | 22/11/2008 | 1. FC Köln | - | 1899 Hoffenheim | 1:3 | ||||
| 20. Round | 13/02/2009 | 1899 Hoffenheim | - | Bayer Leverkusen | 1:4 | ||||
| 26. Round | 04/04/2009 | Hamburger SV | - | 1899 Hoffenheim | 1:0 | ||||
| 27. Round | 11/04/2009 | 1899 Hoffenheim | - | VfL Bochum | 0:3 | ||||
| 28. Round | 18/04/2009 | Karlsruher SC | - | 1899 Hoffenheim | 2:2 | ||||
| 29. Round | 24/04/2009 | 1899 Hoffenheim | - | Hertha BSC | 0:1 | ||||
| 31. Round | 09/05/2009 | 1899 Hoffenheim | - | 1. FC Köln | 2:0 | ||||
| 32. Round | 13/05/2009 | Arminia Bielefeld | - | 1899 Hoffenheim | 0:2 | |
Sweden
