| 8. Round | 12/09/2015 | MFK Skalica | - | Spartak Myjava | 0:0 | ||||
| 9. Round | 19/09/2015 | MŠK Žilina | - | MFK Skalica | 2:2 | ||||
| 10. Round | 22/09/2015 | MFK Skalica | - | FC DAC 1904 | 2:2 | ||||
| 11. Round | 26/09/2015 | AS Trenčín | - | MFK Skalica | 3:0 | ||||
| 12. Round | 03/10/2015 | MFK Skalica | - | MFK Ružomberok | 0:1 | ||||
| 14. Round | 25/10/2015 | MFK Skalica | - | FK Senica | 0:3 | ||||
| 15. Round | 31/10/2015 | FO ŽP Šport Podbrezová | - | MFK Skalica | 3:0 | ||||
| 17. Round | 21/11/2015 | Zlaté Moravce | - | MFK Skalica | 3:1 | ||||
| 18. Round | 28/11/2015 | MFK Skalica | - | Slovan Bratislava | 0:2 |  |
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| 19. Round | 04/12/2015 | Spartak Myjava | - | MFK Skalica | 3:0 | |
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| 21. Round | 02/03/2016 | FC DAC 1904 | - | MFK Skalica | 1:0 | |
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| 22. Round | 05/03/2016 | MFK Skalica | - | AS Trenčín | 1:2 | ||||
| 23. Round | 12/03/2016 | MFK Ružomberok | - | MFK Skalica | 3:1 | ||||
| 24. Round | 20/03/2016 | MFK Skalica | - | MFK Zemplín Michalovce | 0:0 | ||||
| 25. Round | 02/04/2016 | FK Senica | - | MFK Skalica | 2:2 |  |
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| 26. Round | 09/04/2016 | MFK Skalica | - | FO ŽP Šport Podbrezová | 2:1 | ||||
| 27. Round | 16/04/2016 | Spartak Trnava | - | MFK Skalica | 5:1 | ||||
| 28. Round | 19/04/2016 | MFK Skalica | - | Zlaté Moravce | 1:0 |
Slovakia