| 1. Round | 25/08/2018 | PAOK Saloniki | - | Asteras Tripolis | 1:0 | ||||
| 3. Round | 15/09/2018 | OFI Heraklion | - | PAOK Saloniki | 1:3 |  |
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| 4. Round | 23/09/2018 | PAOK Saloniki | - | AEK Athen | 2:0 | ||||
| 5. Round | 30/09/2018 | Olympiakos Piraeus | - | PAOK Saloniki | 0:1 | ||||
| 7. Round | 21/10/2018 | Aris Saloniki | - | PAOK Saloniki | 1:2 | |
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| 8. Round | 29/10/2018 | PAOK Saloniki | - | Panathinaikos | 2:0 | ||||
| 9. Round | 03/11/2018 | Atromitos | - | PAOK Saloniki | 1:1 | |
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| 11. Round | 24/11/2018 | PAOK Saloniki | - | Xanthi FC | 2:0 | ||||
| 12. Round | 03/12/2018 | Lamia | - | PAOK Saloniki | 0:1 | ||||
| 13. Round | 09/12/2018 | PAOK Saloniki | - | AE Lárissa | 2:1 | ||||
| 14. Round | 17/12/2018 | Levadiakos | - | PAOK Saloniki | 1:2 |
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