| 4. Round | 30/04/2022 | SC Paderborn 07 II | - | Westfalia Rhynern | 0:0 | ||||
| 5. Round | 08/05/2022 | SG Wattenscheid 09 | - | SC Paderborn 07 II | 2:1 | ||||
| 6. Round | 15/05/2022 | SC Paderborn 07 II | - | FC Gütersloh | 1:1 | ||||
| 7. Round | 22/05/2022 | SC Paderborn 07 II | - | ASC 09 Dortmund | 8:0 |  |
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| 3. Round | 25/05/2022 | 1. FC Kaan-Marienborn | - | SC Paderborn 07 II | 4:2 | |
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| 8. Round | 29/05/2022 | Sportfreunde Siegen | - | SC Paderborn 07 II | 0:3 | |
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| 9. Round | 06/06/2022 | SC Paderborn 07 II | - | TuS Erndtebrück | 3:1 | |
France
Angola