| 14. Round | 30/10/1980 | FC 08 Homburg | - | SV Darmstadt 98 | 1:7 | ||||
| 16. Round | 14/11/1980 | FC 08 Homburg | - | Hessen Kassel | 0:0 | ||||
| 17. Round | 27/11/1980 | FC Augsburg | - | FC 08 Homburg | 3:5 | ||||
| 18. Round | 05/12/1980 | FC 08 Homburg | - | VfB Eppingen | 1:0 | ||||
| 19. Round | 12/12/1980 | Eintracht Trier | - | FC 08 Homburg | 2:0 | ||||
| 20. Round | 02/01/1981 | Borussia Neunkirchen | - | FC 08 Homburg | 2:1 | ||||
| 23. Round | 23/01/1981 | FC 08 Homburg | - | ESV Ingolstadt | 2:1 | ||||
| 24. Round | 06/02/1981 | Kickers Offenbach | - | FC 08 Homburg | 2:0 | ||||
| 25. Round | 13/02/1981 | FC 08 Homburg | - | Freiburger FC | 2:0 | ||||
| 26. Round | 20/02/1981 | SSV Ulm 1846 | - | FC 08 Homburg | 2:1 | ||||
| 27. Round | 05/03/1981 | FC 08 Homburg | - | SpVgg Bayreuth | 1:3 | ||||
| 34. Round | 23/04/1981 | FC 08 Homburg | - | SC Freiburg | 2:2 | ||||
| 35. Round | 29/04/1981 | Hessen Kassel | - | FC 08 Homburg | 1:0 | ||||
| 37. Round | 14/05/1981 | VfB Eppingen | - | FC 08 Homburg | 0:5 |  |
Iceland