| 1. Round | 19/08/2020 | Alebrijes de Oaxaca | - | Leones Negros | 1:0 | ||||
| 3. Round | 06/09/2020 | Atlante | - | Leones Negros | 0:1 | ||||
| 4. Round | 11/09/2020 | Leones Negros | - | TM Fútbol Club | 1:2 | ||||
| 5. Round | 15/09/2020 | Coyotes de Tlaxcala | - | Leones Negros | 1:3 | ||||
| 7. Round | 02/10/2020 | Club Celaya | - | Leones Negros | 1:0 | ||||
| 10. Round | 19/10/2020 | Cimarrones de Sonora | - | Leones Negros | 2:0 | ||||
| 11. Round | 22/10/2020 | Leones Negros | - | Cancún FC | 0:1 | ||||
| 13. Round | 06/11/2020 | Dorados de Sinaloa | - | Leones Negros | 3:2 | ||||
| 14. Round | 11/11/2020 | Leones Negros | - | Correcaminos UAT | 3:1 |
Mexico