| 1. Round | 19/09/2020 | Saltillo FC | - | Mineros de Fresnillo FC | 2:2 | ||||
| 2. Round | 25/09/2020 | Mazorqueros | - | Saltillo FC | 1:1 | ||||
| 3. Round | 02/10/2020 | Saltillo FC | - | Atlético San Luis II | 1:3 | ||||
| 5. Round | 31/10/2020 | Saltillo FC | - | Gavilanes de Matamoros | 0:0 | ||||
| 9. Round | 21/11/2020 | Colima FC | - | Saltillo FC | 3:0 | ||||
| 4. Round | 29/11/2020 | Reboceros de La Piedad | - | Saltillo FC | 7:0 |
Mexico