| 1. Round | 16/01/2005 | Atlas Guadalajara | - | Santos Laguna | 1:2 | ||||
| 2. Round | 23/01/2005 | Santos Laguna | - | Dorados de Sinaloa | 2:1 | ||||
| 3. Round | 30/01/2005 | CF América | - | Santos Laguna | 4:2 | ||||
| 4. Round | 06/02/2005 | Santos Laguna | - | UAG Tecos | 4:2 | ||||
| 13. Round | 17/04/2005 | Santos Laguna | - | CF Pachuca | 2:0 |
Mexico