| 2. Round | 10/09/2022 | Roda JC Kerkrade [U21] | - | NEC Nijmegen [U21] | 2:3 |  |
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| 3. Round | 17/09/2022 | NEC Nijmegen [U21] | - | Go Ahead Eagles [U21] | 2:1 | ||||
| 13. Round | 06/12/2022 | Twente/Heracles [U21] | - | NEC Nijmegen [U21] | 2:0 | ||||
| 14. Round | 17/12/2022 | NEC Nijmegen [U21] | - | FC Den Bosch [U21] | 2:1 |
Netherlands