| Group B | 24/09/2008 | San Francisco FC | - | Houston Dynamo | 0:0 | ||||
| Group B | 01/10/2008 | Pumas UNAM | - | Houston Dynamo | 4:4 | ||||
| Group B | 08/10/2008 | Houston Dynamo | - | San Francisco FC | 2:1 | ||||
| Group B | 23/10/2008 | Houston Dynamo | - | Pumas UNAM | 1:3 | ||||
| Quarter-finals | 25/02/2009 | Houston Dynamo | - | Atlante | 1:1 | ||||
| Quarter-finals | 04/03/2009 | Atlante | - | Houston Dynamo | 3:0 |
USA