| 1. Round | 21/08/2000 | AFC Ajax | - | Fortuna Sittard | 5:0 |  |
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| 3. Round | 26/08/2000 | Sparta Rotterdam | - | AFC Ajax | 3:0 | ||||
| 4. Round | 05/09/2000 | AFC Ajax | - | NEC Nijmegen | 0:0 | ||||
| 5. Round | 08/09/2000 | AFC Ajax | - | FC Groningen | 3:1 | |
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| 5. Round | 16/09/2000 | AZ Alkmaar | - | AFC Ajax | 3:2 | |
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| 5. Round | 21/09/2000 | AFC Ajax | - | RBC Roosendaal | 2:0 | ||||
| 29. Round | 16/05/2001 | AFC Ajax | - | Vitesse | 1:2 | ||||
| 33. Round | 19/05/2001 | FC Twente | - | AFC Ajax | 1:3 |
Netherlands