| 9. Round | 04/03/2019 | Guaraní | - | River Plate | 2:1 | ||||
| 10. Round | 10/03/2019 | Sol de América | - | Guaraní | 1:4 |  |
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| 11. Round | 17/03/2019 | Guaraní | - | Club Olimpia | 1:5 | ||||
| 12. Round | 23/03/2019 | Cerro Porteño | - | Guaraní | 5:2 | ||||
| 16. Round | 12/04/2019 | Deportivo Capiatá | - | Guaraní | 0:1 | ||||
| 19. Round | 30/04/2019 | Guaraní | - | Deportivo Santaní | 0:0 |
Paraguay