| 1. Round | 19/08/2017 | Nacional | - | Juventud de Las Piedras | 3:0 | ||||
| 3. Round | 02/09/2017 | Nacional | - | Plaza Colonia | 1:0 |  |
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| 5. Round | 17/09/2017 | Nacional | - | Peñarol | 0:2 | |
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| 6. Round | 24/09/2017 | Racing | - | Nacional | 0:1 | ||||
| 7. Round | 15/10/2017 | Nacional | - | El Tanque Sisley | 1:2 | |
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| 8. Round | 04/11/2017 | Liverpool | - | Nacional | 1:4 |  |
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| 9. Round | 09/11/2017 | Nacional | - | Boston River | 5:0 | ||||
| 10. Round | 12/11/2017 | Montevideo Wanderers | - | Nacional | 2:3 | |
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| 11. Round | 15/11/2017 | Nacional | - | CA Cerro | 3:1 | |
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| 14. Round | 26/11/2017 | Nacional | - | Defensor Sporting | 1:1 |
Uruguay