| 5. Round | 15/08/2020 | Deportivo Guadalajara [U20] | - | Atlético San Luis [U20] | 7:1 |  |
|||
| 7. Round | 29/08/2020 | Deportivo Guadalajara [U20] | - | CF Pachuca [U20] | 3:2 |  |
|||
| 11. Round | 19/09/2020 | CF América [U20] | - | Deportivo Guadalajara [U20] | 1:2 | ||||
| 4. Round | 07/10/2020 | FC Juárez [U20] | - | Deportivo Guadalajara [U20] | 2:1 | ||||
| 15. Round | 25/10/2020 | Deportivo Guadalajara [U20] | - | Cruz Azul [U20] | 1:1 | |
|||
| 16. Round | 31/10/2020 | Pumas UNAM [U20] | - | Deportivo Guadalajara [U20] | 2:1 | ||||
| 17. Round | 07/11/2020 | Deportivo Guadalajara [U20] | - | CF Monterrey [U20] | 1:2 | ||||
| 2. Round | 13/11/2020 | Santos Laguna [U20] | - | Deportivo Guadalajara [U20] | 2:2 |
Mexico