| 2. Round | 15/08/2010 | Huracán | - | River Plate | 0:1 | ||||
| 4. Round | 29/08/2010 | Argentinos Juniors | - | River Plate | 0:0 | ||||
| 6. Round | 12/09/2010 | River Plate | - | Arsenal de Sarandí | 1:0 | ||||
| 7. Round | 19/09/2010 | Newell's Old Boys | - | River Plate | 1:0 | ||||
| 12. Round | 23/10/2010 | River Plate | - | Racing Club | 1:1 | ||||
| 13. Round | 07/11/2010 | All Boys | - | River Plate | 1:0 |
Paraguay