| 12. Round | 16/09/2021 | Uruguay Montevideo | - | Racing | 1:2 | ||||
| 13. Round | 22/09/2021 | Racing | - | Rampla Juniors | 2:0 | ||||
| 14. Round | 29/09/2021 | Danubio | - | Racing | 2:0 | ||||
| 15. Round | 06/10/2021 | Racing | - | Rocha | 3:0 |  |
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| 16. Round | 14/10/2021 | CA Cerro | - | Racing | 1:0 | |
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| 17. Round | 20/10/2021 | Racing | - | Defensor Sporting | 0:1 | |
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| 18. Round | 28/10/2021 | Central Español | - | Racing | 1:1 | ||||
| 19. Round | 02/11/2021 | Racing | - | Atenas | 0:0 | |
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| 20. Round | 09/11/2021 | Racing | - | Albion | 1:1 | ||||
| 21. Round | 17/11/2021 | Villa Teresa | - | Racing | 0:0 |
Uruguay