| 27. Round | 27/02/2021 | Irtysh Omsk | - | FK Neftekhimik | 1:2 | ||||
| 30. Round | 14/03/2021 | Alania Vladikavkaz | - | FK Neftekhimik | 1:1 | ||||
| 31. Round | 20/03/2021 | Tekstilshchik Ivanovo | - | FK Neftekhimik | 0:1 | ||||
| 32. Round | 24/03/2021 | Krylia Sovetov | - | FK Neftekhimik | 2:0 | ||||
| 34. Round | 03/04/2021 | Fakel Voronezh | - | FK Neftekhimik | 1:1 | ||||
| 35. Round | 07/04/2021 | FK Neftekhimik | - | Shinnik Yaroslavl | 1:1 | ||||
| 36. Round | 11/04/2021 | FK Neftekhimik | - | Torpedo Moskva | 2:2 | ||||
| 37. Round | 17/04/2021 | FK Neftekhimik | - | Akron Tolyatti | 3:2 | ||||
| 40. Round | 02/05/2021 | Veles Moskva | - | FK Neftekhimik | 0:2 | ||||
| 41. Round | 08/05/2021 | FK Neftekhimik | - | SKA-Khabarovsk | 3:2 | ||||
| 42. Round | 15/05/2021 | FK Chayka | - | FK Neftekhimik | 1:0 |  |
Russia